Tuesday, January 17, 2012

High blood pressure, anemia put sickle cell kids at risk for strokes

A team of researchers from the Johns Hopkins Children’s Center, Vanderbilt University and elsewhere have demonstrated that high blood pressure and anemia together put children with sickle cell disease at serious danger for symptomless, or “silent,” strokes, although either condition alone also signaled high risk.
The results are part of an ongoing National Institutes of Health–funded international multicenter trial, believed to be the largest study of its kind to date in children with sickle cell disease, or SCD. A report on the findings was published online Nov. 17 in the journal Blood.
In the study, brain MRI scans revealed that nearly a third (31 percent) of 814 children, ages 5 to 15, had suffered silent strokes. None of the children had a history of stroke or seizures, and none showed overt stroke signs at the time of the study.....Next